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ea0026p232 | Pituitary | ECE2011

Copeptin in the differential diagnosis of the polydipsia–polyuria syndrome: revisiting the direct and indirect water deprivation tests

Fenske W K , Quinkler M , Haagen U , Papassotiriou J , Pfeiffer A F H , Fassnacht M , Stoerk S , Allolio B

Background: The water deprivation test (WDT) with direct or indirect measurement of plasma vasopressin (AVP) is the method of choice for the differential diagnosis of the polydipsiapolyuria syndrome. In theory, direct measurement of AVP is highly attractive but hampered by technical difficulties.Objective: To evaluate the utility of copeptin, a surrogate of AVP secretion, in the diagnostic work-up of the polyuriapolydipsia syndrome, and to co...

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ea0029p790 | Endocrine tumours and neoplasia | ICEECE2012

The influence of surgery in the management of recurrent adrenocortical carcinoma.

Deutschbein T. , Erdogan I. , Jurowich C. , Kroiss M. , Quinkler M. , Langer P. , Willenberg H. , Beuschlein F. , Fottner C. , Klose S. , Heidemeier A. , Brix D. , Fenske W. , Hahner S. , Reibetanz J. , Allolio B. , Fassnacht M.

Objective: The role of surgery for recurrent adrenocortical carcinomas (ACC) is not well defined. Therefore, we evaluated the outcome after surgery for tumor recurrence in patients from the German ACC Registry.Methods: Only patients with first recurrence after initial R0 resection were investigated. Progressionfree and overall survival (PFS, OS) after first recurrence were analyzed by KaplanMeier method. Cox proportional hazards regression mo...

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Endocrine Abstracts

Copeptin in the differential diagnosis of the polydipsia–polyuria syndrome: revisiting the direct and indirect water deprivation tests

The influence of surgery in the management of recurrent adrenocortical carcinoma.

BiosciAbstracts